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Guttate Psoriasis Pack

Guttate Psoriasis Pack
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Acne is common in adolescents and young adults. It usually occurs in early adolescence and decreases after the age of 25. However, some people, particularly women, develop acne for the first time in their late twenties or thirties. Severe acne tends to run in families and is presents more often in males.

Acne may also develop in people who suffer from any of several endocrine disorders. In particular, acne may develop in people who have abnormalities in circulating androgens. Some drugs can also cause or make acne worse.

Acne is a chronic inflammatory disease of the sebaceous (oil) glands and hair follicles.The scattered lesions caused by acne can manifest as single or multiple bumps generally called nodules or papules. Acne generally appears on the face (especially the chin, cheeks, forehead and around the nose), the chest, back, buttocks, nape, and scalp. Involvement is often symmetrical. Increased sebaceous activity on the face and scalp also leads to an oily complexion and greasy hair.

Acne is most likely caused by a combination of factors. First, there is an increase in sebum production and a blockage of the hair follicle. With the follicle blocked the population of normal bacteria in the follicle increases dramatically. The bacteria produce inflammatory chemicals, which leak into the surrounding dermis (skin).

Where the pore opening is large, the semisolid mass of debris creates a “plug” and appears at the skin surface as a blackhead. Whiteheads occur where the pore opening is small and the follicle walls then distend. Eventually this breaks allowing the mass of sebum, lipids, fatty acids and keratin to enter the dermis (skin layers). This then provokes a “foreign body” response and the formation of papules, pustules and nodules occurs. It is the rupturing of these that leads to intense inflammation of the skin. Continual occurrences in the same area will lead to scarring.

Although acne usually disappears once adolescence and growth are over, it can persist into adulthood. Women often present with acne during their menstrual cycle. It can also reappear in later years, especially in women who have received hormone treatment for other conditions.

In some cases, mostly males, papules can develop into red or dark red nodules or cysts which are located deeper within the skin than the normal presentation of papules. The surface area of the cysts are larger and malleable upon palpitation with the fingers. This form of acne usually leads to deep pitted scarring.